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Research
The iGrow Hair Growth System has been verified by thorough research, and Apira Science has conducted separate clinical studies for both men and women. Please see below for Published Abstracts.
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Women's Clinical Study
Lasers in Surgery and Medicine 46:601—607 (2014)
Title
The Growth of Human Scalp Hair in Females Using Visible Red Light Laser and LED Sources. Lanzafame RJ, Blanche RR, Chiacchierini RP, Kazmirek ER, Sklar JA.
Abstract
Background and Objectives
Background and Objectives: Low-Level Light Therapy (LLLT) has been demonstrated to promote hair growth in males. A double-blind randomized controlled trial was undertaken to define the safety and physiological effects of LLLT on females with androgenetic alopecia.
Methods
Forty Seven women between the ages of 18-60 with Fitzpatrick Skin Types I-IV and Ludwig-Savin Baldness Scale I-2—II-2 baldness patterns were recruited. A transition-zone scalp site was selected; hairs were trimmed to 3 mm height; the area was tattooed and photographed.

The active group received a “TOPHAT655” (iGrow unit) unit containing 21, 5 mW lasers (655 +/- 5 nm), and 30 LEDS (655 +/- 20 nm), in a bicycle helmet-like apparatus. The placebo group unit appeared identical, containing incandescent red lights. Patients treated at home every other day for 16 weeks (60 treatments, 67.3 J/cm(2) irradiance/ 25-minute treatment), with follow-up and photography at 16 weeks. A masked 2.85 cm(2) photographic area was evaluated by another blinded investigator. The primary endpoint was the percent increase in hair counts from baseline.
Results
Forty-two patients completed the study (24 active, 18 sham). No adverse events or side effects were reported. Baseline hair counts were 228.2_133.4 (N.18) in the sham and 209.6_118.5 (N.24) in the active group (P.0.642). Post-treatment hair counts were 252.1_143.3 (N.18) in the sham group and 309.9_166.6 (N.24) in the active group (P.0.235). The change in hair counts over baseline was 23.9_30.1 (N.18) in the sham group and 100.3_53.4 (N.24) in the active group (P<0.0001). The percent hair increase over the duration of the study was 11.05_48.30 (N.18) for the sham group and 48.07_17.61 (N.24) for the active group (P<0.001). This demonstrates a 37% increase in hair growth.
Conclusions
LLLT of the scalp at 655nm significantly improved hair counts in women with androgenetic alopecia at a rate similar to that observed in males using the same parameters.
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Men's Clinical Study
Lasers Surgery and Medicine 2014 Apr; 46(4):373.
Title
The Growth of Human Scalp Hair Mediated By Visible Red Light Laser and Led Sources In Males. Lanzafame RJ, Blanche RR, Bodian AB, Chiacchierini RP, Fernandez-Obregon A, Kazmirek ER
Abstract
Background and Objectives
Low-Level Light Therapy (LLLT) has been used to promote hair growth. A double-blind randomized controlled trial was undertaken, to define the safety and physiologic effects of LLLT on males with androgenic alopecia.
Methods
Forty-four males (18-48 yo, Fitzpatrick I-IV, Hamilton-Norwood IIa-V) were recruited. A transition-zone scalp site was selected; hairs were trimmed to 3 mm height; the area was tattooed and photographed. The active group received a “TOPHAT655” unit containing 21, 5 mW lasers (655 +/- 5 nm), and 30 LEDS (655 +/- 20 nm), in a bicycle-helmet like apparatus. The placebo group unit appeared identical, containing incandescent red lights. Patients treated at home every other day for 16 weeks (60 treatments, 67.3 J/cm(2) irradiance/25-minute treatment), with follow-up and photography at 16 weeks. A masked 2.85 cm(2) photographic area was evaluated by another blinded investigator. The primary endpoint was the percent increase in hair counts from baseline.
Results
Forty-one patients completed the study (22 active, 19 placebo). No adverse events or side effects were reported. Baseline hair counts were 162.7 +/- 95.9 (N = 22) in placebo and 142.0 +/- 73.0 (N = 22) and active groups respectively (P = 0.426). Post-treatment hair counts were 162.4 ± 62.5 (N = 19) and 228.7 +/- 102.8 (N = 22), respectively (P = 0.0161). A 39% percent hair increase was demonstrated (28.4 +/- 46.2 placebo, N = 19; 67.2 +/- 33.4, active, N = 22) (P = 0.001) Deleting one placebo group subject with a very high baseline count and a very large decrease, resulted in baseline hair counts of 151.1 +/- 81.0 (N = 21) and 142.0 +/- 73.0 (N = 22), respectively (P = 0.680). Post-treatment hair counts were 158.2 +/- 61.5 (N = 18) and 228.7 +/- 102.8 (N = 22) (P = 0.011), resulting in a 35% percent increase in hair growth (32.3 +/- 44.2, placebo, N = 18; 67.2 +/- 33.4, active, N = 22) (P = 0.003).
Conclusions
LLLT of the scalp at 655 nm significantly improved hair counts in males with androgenetic alopecia.
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Men
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Women
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